Ass 3 Essay Example | Topics and Well Written Essays - 250 words

Ass 3 - Essay Example It cost the firm $180,500 to create the ad. A Mexican Company, Avocado also runs its commercials during Super Bowl events. Last year, the firm advertised a warm-weather fruit during the middle of winter. In a press release, the firm reported that it sold more than 70 million avocados in the United States. Avocado Mexico spends about $70,000 to create ads (OReilly & Lutz, 2015). McDonalds’s that has recently undergone a huge marketing refresh bids to turn around its sales. The firm has created a one-minute spot in order to promote its new ‘Pay with Loving Promotion.’ It cost the firm $130,000 to create the ad. The company would be selecting participants for the ‘Pay with Loving’ at some of its stores. The firm aims at increasing its sales. To that effect, during the Super Bowl match pitting Seahawks and New England Patriots an estimated 110 million people watched the game (LeBeau, 2015). Therefore, the advertisers expected their products to be known to the more than 100 million people who were watching the match. An increase in product awareness may result in increased sales. However, the Super Bowl ads are only limited to American broadcasts. All the three firms: Avocado Mexico, Coca-Cola, and McDonald’s created 60-second. The cost of creating a 30-minute advert is about $37,500 in Super Bowl and $4.5 million in Super Bowl XLIX. It implies that the cost of a one-minute commercial is between $76,000 and $9 million in Super Bowl and Super Bowl XLIX, respectively. Coca-Cola used $740,000, Macdonald’s $240,000, and Avocado Mexico $100,000 (OReilly & Lutz, 2015). Considering the huge crowds that follow Super Bowl, most firms expect the huge viewership to translate into sales due to expanded customer base. In 2015, the game’s viewership was at a record 114.4 million. The companies expect to recoup their costs from the resulting revenue. However, the

The Exploration and drilling process Research Paper

The Exploration and drilling process - Research Paper Example However since technology is known to be dynamic this research paper recommend that other research papers similar to this should be conducted every now and then to encompass the new impacts emerging. Several authors have discussed the process of oil exploration in various contexts. Ofstad (20)explained thatnew models should be establishedwith new discoveries experiencedin new exploration.Poletto and Miranda (1), showed that oil and gas exploration consists of three main phases that are the geophysical exploration with geological interpretation of processed data, drilling phase and production phase. However, Bjorndal (56) explained that the typical pattern for individual fields, regions and provinces is that exploration activities uncover more oil reserves than predicted by the geophysical approach. Hyne (233) discussed the drilling preliminaries, the mechanics for drilling an oil well, the drilling problems and the drilling techniques. However, none of the scholars relates the current technological advancement with the improvements in the process of oil exploration and drilling. This is the reason why I have decided to undertake this research so that I can indicate the various progresses that have been achieved in the process of oil exploration and drilling because of improvement in the levels of technology. One of my specific objectives is to explore how technology has improved the collection, analysis and interpretation of seismic data in determining the presence of oil deposits. My other specific objective is to determine how technology has influenced the process of oil drilling and various preparations involved as well as the choice for the equipment to use during the process. The process of oil exploration involves three phases. The first phase is geophysical explorations with geological interpretation of geological data. This phase identifies a geological region in which to drill oil wells and after a

Finding the Gravitational Constant: Cavendish Experiment

Finding the Gravitational Constant: Cavendish Experiment Matt Cramb    The experiment explored the story of gravity, how it was discovered and derived from observations and experimentations, and attempted to recreate those initial tests. This was done to determine whether an increase in mass will increase the force of gravity, a statement which was supported by the experimental data, despite the numerous flaws inherent in the experimental design. Finding Gravity Gravity is one of the four fundamental forces of nature, and Nave, R (2017) also explains that it is the force responsible for constructing and regulating the movement of galaxies, stars, and planets. In 1687, Isaac Newton formulated his famous Equation of Universal Gravitation based, purported by Physics Classroom (2016), on an injury in an apple orchard. Whatever the circumstances, it had far reaching impacts on the science of the time. But something crucial was missing from his equation. Newton knew from scientists before him that the force exerted by gravity grew weaker as distance between objects affected by gravity increased, or represented mathematically; Where: This was nothing new for science of the time, but Newtons major discovery was that of the universality of gravity, which indicated that all objects which possess mass also exerted gravitational forces. This discovery led to another addition to the equation, because Kurtus, R (2016) reports Newton realized that objects with less mass exerted weaker gravitational forces. Therefore, he postulated that; Where: To convert this theory into an equation, Newton only needed one more piece. A constant was needed to calculate the exact gravitational forces on objects. This constant was called the gravitational constant, or G. In the equation, G presents as follows: However, the value for G wasnt found until much later, by Lord Henry Cavendish, over a century later.       The Cavendish Experiment In Cavendishs experiment, according to Shectman, J (2003) two spheres were attached at opposite ends of a beam which is suspended from the ceiling of a custom-built shed by a thin wire. Masses are placed to the sides of the spheres, to attract them, exerting gravitational forces sufficient to rotate the beam to a measurable degree. Cavendish measured the movement of the beam using a telescope positioned far from the shed. To use this apparatus to calculate G, a formula must be created, using torque, oscillation period, torsion constant, inertia and gravitational forces. The torque on the beam can be measured by the angle of deflection of the torsion wire, using Hookes Law: Where: However, torque can also be measured by the following expression: Where: Torque can also be calculated as a vector product with this equation: Where: And because, in this experimental setup, r and F are perpendicular vectors, there are two F, and r is half the length of the beam: Combining these two formula together results in the following: From Newton, the formula for force was also known, and could be substituted in from above. The torsion constant was measured by Cavendish by disturbing the beam, then measuring the period of oscillation. This can be done using the below equation. Where: This moment of inertia can be calculated from the sum moments of the two spheres at each end of the beam. The moment of inertia for each sphere is calculated by the equation: Since each sphere had equal mass, the total I is equal to: Inserting this into the period formula and rearranging for the torsion coefficient gives: When inserted into the formula for torsion coefficient above, gives the following: With this equation, the measurements needed to be taken from the experimental apparatus are: Variable: Explanation: Units: m Rad m kg s Using the experimental setup described above, according to Kurtus, R (1997) Cavendish determined: Preliminary Trials Failed Attempts For this experiment, two previous iterations of the experiment were run. The first was to determine the validity of running such an experiment, and the second was a full-scale experiment which provided no useful data. The first experiment was done using a meter-long beam and tennis balls attached to either end. A laser beam reflected off a mirror attached to the torsion wire, giving a result of angle. However, in practice, this rig did not come to a final resting position so that the period of oscillation could be measured. Instead the torque already present in the twine torsion wire twisted the beam against a chair leg, preventing it from fully coming to a balance of forces. The second experiment had results as follows: Variable: Explanation: Units: Results: m 1.25ÃÆ'-101 Rad 9.0ÃÆ'-10-2 m 1.765 kg 1.6 s 2.25ÃÆ'-102 m3kg-1s-2 2.419ÃÆ'-102 The value for G calculated by this experiment was vastly different to Cavendishs value of . This meant the experiment was concluded to be not statistically valid, for a variety of reasons. These experiments were refined and transformed into the final experimental setup. Theoretical Data Using Newtons formula for each of the three experiments which will be conducted can determine the value for . To do this, the masses and distance must be known ahead of time. These can be found below, and copied in the results section. OBJECT MASS (kg) Mass of Sinkers Mass of Cup 1 Mass of Cup 2 Mass of Bowling Pins Using Cavendishs above listed value of G, the projected data can be calculated. MASS (kg) FORCE OF GRAVITY ( Later, these will be compared with the experimental data. Based on the above background research, the magnitude of gravity in the system will increase proportional to an increase in the mass of the large masses. Or, as increases, will proportionally increase. This hypothesis has been supported by the background research, which has guided its creation through empirical data, and researched phenomena. However, because of the precision required to obtain an accurate result, research indicates the final calculated measurement for G will be vastly different from the real value. 25.5cm support beam12cm length of fishing line2x sinkers of mass 3.28g2x plastic cups2x bowling pins of mass 1.6kg1x stopwatch1x ruler1x camera1x plastic storage box approx. 70cm x 40cm 1m2 wire mesh Safety Before the experiment was conducted, a thorough risk assessment planner was completed and approved. Measures were taken to ensure no harm came to experimenter through heavy masses falling or water causing a slipping hazard. These measures included: Constant supervision Correct and appropriate use of safety equipment, which in this experiment meant wearing a lab coat throughout Safe handling of heavy masses and water. A risk assessment matrix provided by the Department of Education (2017) was also completed. Likelihood Consequence Insignificant Minor Moderate Major Critical Almost Certain Medium Medium High Extreme Extreme Likely Low Medium High High Extreme Possible Low Medium High High High Unlikely Low Low Medium Medium High Rare Low Low Low Low Medium The likelihood of injury was unlikely, as experimenter has previous experience. The consequence was also minor, indicating injuries not requiring medical attention (i.e. bruises, minor cuts). Therefore, the total risk was low, which indicates no further control measures need be put into place. However, in due diligence the above measures were still implemented. Procedure Firstly, to limit air flow; a major disturbance in the preliminary trials, the system was constructed inside a large plastic storage container. This container was placed a distance away from walls, to reduce the effects of other gravity sources. Then, two sinkers, whose masses were known, were attached to either end of a support beam, which was hung from the top of the box by a length of fishing line. This was suspended by the wire mesh atop the box. The fishing line was chosen as twine had been used in preliminary trials as the torsion wire, and had been shown to not be effective due to the latent torque. After letting the system come to a complete rest, it was disturbed by gently pushing one end of the support beam. The period of oscillation was measured by a stopwatch. To further reduce misrepresentation of data, six measurements were taken and averaged. The system was then allowed to come to rest again, and a measurement of the rest position taken by a camera from above. This would eliminate the need to reach into the box to take measurements and thus disturb the experiment. It also provided clearer results. Then, the two cups were introduced to the system 6.25cm away from the end of the support beam, at opposing sides and ends, so the attractive forces of the masses rotated the beam. The cups were initially filled with 250g of water, then 500g, then the cups were swapped with the 1.6kg bowling pins. Each iteration of the experiment, when the system came to rest for a third time, a measurement of the final rest position was taken using the camera. This data was recorded and processed by comparing photographs of the different rest positions and calculating angle of deflection. The results were then tabulated. Images of the experimental setup. Mass OBJECT MASS (kg) Mass of Sinkers Mass of Cup 1 Mass of Cup 2 Mass of Bowling Pins Period of Oscillation TEST NUMBER PERIOD (s) 1 20 2 22 3 21 4 21 5 21 6 21 Avg. 21 Rest Position TEST NUMBER MASSES USED ANGLE OF DEFLECTION (Rad) 1 No mass used 0.00 2 Cup 1 9.65 3 Cup 2 3.31 4 Bowling Pins 1.00 OTHER Data Variable: Explanation: Units: Results: m 0.0625 m 0.255 Magnitude of Gravity Using Newtons formula for each of the three experiments will determine the value for . Firstly, the value for G for each equation must be calculated. MASS (kg) VALUE OF G ( Now the force for gravity can be calculated. MASS (kg) FORCE OF GRAVITY ( findings The experiment shows that using Cavendishs method to determine the value for G was flawed, but that the experiment could have obtained an accurate value for G. These flaws will be examined below, but a basic rundown and description of data obtained will be given here. Magnitude of Gravity As can be seen by the graph at the end of the results section, the magnitudes of gravity measured do not accurately match the theoretical data obtained. These values, and the values for G, are vastly different to that originally measured by Cavendish (found in background research), likely because of the various flaws in the experimental design, which will be discussed in the Evaluation section. However, the results far more accurately correlate to the theoretical values than those in previous experiments, and the average trendlines do indicate that the trend matches that predicted. At 250g, the first mass, the experimental data differs wildly from the theoretical. Experimental Data Theoretical Data At 500g, the second mass, it drastically spikes, much higher than either of the other points. Experimental Data Theoretical Data At 1600g, the final point, the data dips down lower than expected again. Experimental Data Theoretical Data Its unclear from the background research conducted whether Cavendishs data deviated so much, but he also had a larger rig, which as discussed below, may have helped his experiments accuracy. Period of Oscillation The average period measured was 21 seconds, which is far shorter than the fifteen minutes measured by Cavendish. This is probably mostly due to the shorter beam, the effect of which can be seen with the torsion coefficient formula derived from the background research. The squared length of the beam demonstrates an exponential relationship between the torsion coefficient, an increase in which will decrease the period, which can be seen in the following formula for period of oscillation: Recording Equipment The equipment used to measure the period of oscillation may not have changed in the two hundred years since Cavendishs original experiment, however all other recording equipment did. A camera and digital analysis was used to take measurements, which may have causes slight issues with the orientation of frames in the software, but overall was more accurate than taking the measurements by hand when compared to the preliminary tests when this was done. The lengths were taken with a tape, and so were only calculated to two decimal places. However, this will likely not impact greatly on the results of the experiment, which can be shown mathematically. Using the same formula as above, and two length measurements as given below, the difference can be theorised. cm Value for k K (2 decimal places) Length 1 (two decimal places) (given by experiment) 6.25 2.35497 2.35 Length 2 (six decimal places) 6.247832 2.35334 2.35 Limitations Recommendations There are several reasons for why the value for G determined by this experiment differed so greatly from Cavendishs value, and these expose various flaws and strengths in the original design. They will be examined each using the following method: Name Explanation of Flaw Effects Comparison to Preliminary Trials Comparison to Cavendish Experiment Recommendation/Refinement Measuring Inaccuracies Various opportunities for error arose when observing and recording data in the experiment. Most of these examples, such as misreporting the period of oscillation by a fraction, would have a m Ethical Issues in Patient Information | Case Study Ethical Issues in Patient Information | Case Study Peeking in the EMR for all the right reasons Patrick Bobst Technology has embedded itself into everyday life and is integrated into everyday human activity. Corporate scandals, violations of intellectual property rights, and violations of customer, patient, employee privacy is uncovering challenging dilemmas and ethical decision-making in every the industry around the globe. Technological advancements not only increase the impact of carelessness, foolishness, recklessness and even malevolence but also enable anyone with access to learn much more and much faster than ever before(Curtain, 2005). Ethics enables individuals with the guidance of rational approaches to make the right justifiable decision. Ethical choices distinguished from other choices involve the continual conflict of fundamental values, as well as incorporating scientific inquiry that may be influential but cannot provide answers(Curtain, 2005). Most notably, ethical choices involve placing one value above another, and because values are of the utmost importance, any decision r eached will have profound, multiple and often on anticipated impact on human concern(Curtain, 2005). Case study Jessica Parker is a nurse that has the burdening task to solely support her three small children and is in severe financial distress since her divorce. Her ex-husband, Frank Parker has evaded court ordered child support obligations for over a year and has been able to evade authorities with no known address or phone number. Jessica’s house is about to be foreclosed upon, and her automobile repossessed. Although Jessica periodically picks up extra shifts, utilizes friends instead of childcare, and despite making multiple drastic cuts to her budget, she is unable to overcome the perils of increasing debt. One day a friend that informs her that Frank Parker received stitches in her emergency department after a minor motor vehicle accident (MVA). The next day she worked Jessica looked up her ex-husband in the EMR and proceeded to gather his needed contact information. Jessica immediately passes along the phone number, living address and employment information to her attorney which in turn succeeded in the actions of court ordered child support payments being automatically garnished from his wages along with a judgment for past due child support in an amount that will stabilize her current debt. Ethical dilemma When a couple chooses the responsibilities of being a parent, it is a commitment for life whether they are living together or separately. Jessica is in a stressful environment where she holds the custody of the children and the other parent is legally obligated to provide financial support to ensure a safe and healthy environment for the children. Jessica is clearly struggling financially and the situation will continue to worsen without the court ordered child support from ex-husband. She solved the dilemma of finding her ex-husband’s whereabouts by utilizing the hospitals EMR. By utilizing the EMR in an inappropriate manner, Jessica violated multiple provisions of the American Nurses Association (ANA) code of ethics including provision 3.1, 3.2, and 3.3. These provisions stipulate the patient’s right to privacy, the duty to maintain confidentiality of all patient information, and the protection of participants in research(Nursing World website, 2011). A breach of the Health Insurance Portability and Accountability Act (HIPAA) may have been committed under the privacy rule where â€Å"patients have a right to expect privacy protections that limit the use and disclosure of their health information†(McGonigle Mastrian, 2012, p. 173). â€Å"However, the privacy rule permits unauthorized disclosures of protected health information to public health authorities for specified public health activities including†¦. child abuse or neglect†(Lee Gostin, 2009, p. 82). Possible Alternatives At the point when Jessica suspected her husband might have been in the EMR system, an alternate path might be (1) hiring a private investigator. The ex-husbands MVA is a matter of police public record and private investigators are trained and have the resources to find information in ways others might not think about; (2) contact the local child support enforcement agency with the information of the MVA; (3) contact her attorney for a medical record subpoena. Hypothesize Ethical Arguments In this scenario, Jessica showed a clear breach to hospital policy, statutory and common-law duties of confidentiality and privacy. However, Jessica’s morals were dealing with the resolution of what is right and wrong in her own situation creating the dilemma of what is morally right and not looking at the evidence that indicates that she is also morally wrong. Depending on the discipline and point of view, the term value can have different meanings. Jessica’s objective moral values may include justice, freedom and welfare, which might be her basis for decision-making. The welfarism normative ethical approach applies to Jessica situation where morality is viewed and centrally concerned with the welfare or well-being of individuals, and where advancing the best interests of individuals makes the most fundamental sense(Keller, 2009). The ethical theoretical Principlistic approach validates itself with its universally recognized moral principles of autonomy, nonmaleficence , beneficence, and justice(Bulger, 2009). Autonomy considers the right of the individual to choose for themselves, nonmaleficence asserts an obligation not to inflict harm intentionally, beneficence refers to actions performed that contribution to the welfare of others, and justice refers to the fair, equitable, and appropriate treatment in light of what is due or owed to a person(McGonigle Mastrian, 2012). â€Å"Principlism is a unified moral approach in which the addition of each principal strengthens the legitimacy of each of the other principles to the extent that each principal is specified and balanced using independent criteria and yet each principal still supports each of the other principles†(Bulger, 2009, p. 121). In Jessica’s scenario she might consider that it is generally morally right to obtain her ex-husbands contact information in the EMR because this action obeys the role moral rule what is due or owed which in turn is derived from the principal justi ce. The crux of the dilemma lies within Jessica’s responsibility of providing her family a safe and healthy environment with financial stability, her utilization of the hospitals EMR balanced with her ex-husband’s medical record confidentiality rights. Investigate, Compare, and Evaluate Alternatives to him In Jessica’s case, there is no ambiguity in our nursing code of ethics when it comes to maintaining patient privacy and confidentiality. All the alternative methods provided to pursue the coveted contact information are the only acceptable legal pathways. These alternative methods safeguard patient rights, do not violate policy and laws, do not result in bad consequences, nor do they nullify rules and regulations. Each alternative provides expected outcomes that far exceed the risk of harm that include â€Å"civil liability, job loss, disciplinary action by state licensing boards, and even criminal investigations and sanctions†(Hader Brown, 2010, p. 270). Chosen alternative Simply from a financial standpoint the alternative chosen for Jessica would be to contact the local child support services agency. Hiring a private investigator or attorney can be cost prohibitive especially with her financial difficulties. Conclusion From nursing school until retirement, nurses are taught there is no leeway when it comes to HIPAA’s integrity and confidentiality of patient information. A problem with ethics is the logic of reasoning being used in moral deliberation and moral justification(Reidl, Wagner, Rauhala, 2005). Jessica’s deliberation of moral reasoning resorted from weighting only the positive self-fulfilling gain and omitted possible alternatives in her morally perplexing situation as well as her personal reasons in moral justification. Principlists consider principles to be at the heart of moral life negotiating between the four fundamental principles and the unique nature of specific moral situations on the other(McCarthy, 2003). With the technological advancements in today’s society the ethical questions evolve around how individuals choose to use or abuse their tools. Healthcare informatics intersects healthcare, ethics and informatics and all practitioners, for the publicâ€℠¢s good, must be bound by additional ethical, moral, and legal responsibilities (Curtain, 2005). Barrie Effy (2008), conclude in their study that ethical education in information technology changed attitudes and aided students in affective learning, an important and necessary component in the overall learning process(Barrie Effy, 2008). References Barrie, L., Effy, O. (2008). Ethical issues in information technology: Does education make a difference. International Journal of Information and Communication Technology Education, 4(2), 67-83. http://dx.doi.org/10.4018/jicte.2008040106 Bulger, J. W. (2009). An approach towards applying principlism. Ethics Medicine, 25, 125-125. Curtain, L. L. (2005). Ethics in informatics. Nursing Administration Quarterly, 29, 349-352. http://dx.doi.org/10.1097/00006216-200510000-00010 Hader, A., Brown, E. (2010). Patient privacy and social media. American Association of Nurse Anesthetists, 78, 270-274. Retrieved from http://www.aana.com/newsandjournal/Documents/legbrfs_0810_p270-274.pdf Keller, S. (2009). Welfarism. Philosophy Compass, 4(1), 82-95. http://dx.doi.org/10.1111/j.1747-9991.2008.00196.x Lee, L., Gostin, L. (2009). Ethical collection, storage, and use of public health data: A proposal for a national privacy protection. The Journal of the American Medical Association, 302(1), 82-84. http://dx.doi.org/10.1001/jama.2009.958 McCarthy, J. (2003). Principlism or narrative ethics: must we choose between them? Medical Humanities, 29(2), 65-71. http://dx.doi.org/10.1136/mh.29.2.65 McGonigle, D., Mastrian, K. G. (2012). Nursing informatics and the foundation of knowledge (2nd ed.). Burlington, MA: Jones and Bartlett. Nursing World website. (2011). http://www.nursingworld.org/MainMenuCategories/EthicsStandards/CodeofEthicsforNurses/Code-of-Ethics.pdf Reidl, C., Wagner, I., Rauhala, M. (2005). Examining ethical issues of IT in healthcare. Retrieved from http://www.sfu.ca/act4hlth/pub/working/Ethical-Issues.pdf

Does Playing Violent Video Games Promote Aggressive Behavior? Essay exa

Introduction Violent video games are becoming more popular among children and adolescents of all ages since its debut approximately 30 years ago. This growing popularity is generating an increasing concern that these sometimes very graphic videos and life like characters can have a negative influence on the younger generation. Although never proven, there has been speculation that some of the high school shootings across the country were committed by students who were habitual players of violent video games. Due to these concerns, a non-profit, self-regulatory organization was established in 1994 by the Entertainment Software Rating Board (ESRB) to appropriately rate all video games from EC (early childhood), E (everyone), E10+ (everyone 10 and over), T (teen), M (mature), and AO (adults only). While assessing the efficacy of violent video game ratings, it is unknown how effective these ratings are for the intended audience (Becker-Olsen & Norberg, 2010). The purpose of this paper is to present a literature review on existing articles relating to the possibility of violent video games promoting aggressive behavior. The hypothesis set forth was that people who played non-violent video games displayed more Prosocial behavior versus those who played violent video games displayed more antisocial and aggressive behavior. A search was conducted on regular search engines on the internet, and on EBSCOhost using the title â€Å"can violent video games promote aggressive behavior.† The research articles presented are obtained from five case studies each focusing on different measures that were obtained, methods used, the participants involved, the designs of the study, and the results of the studies. Measures Demonstrating Viole... .... DOI: 10.1080/10888690903288748. Retrieved from EBSCOhost Research Database. Polman, H., Orobio De Castro, B. & Van Aken, M. A.G. (2008). Experimental Study of the Differential Effects of Playing Versus Watching Violent Video Games on Children’s Aggressive Behavior. Wiley-Liss Inc. Interscience. Doi: 10.1002/ab.20245. Retrieved from EBSCOhost Research Database. Saunderson, Matt (August 17th, 2005). The American Psychological Association says violence in Videogames is bad for children’s health. Kombo.com. Retrieved from http://ps3.kombo.com/ Article.php?artid=1760. Suhn Lee, M., & Barr, R. (August 2004,). Effects of Video Game Violence on Prosocial and Antisocial Behaviors. Journal of Young Investigators, 11(2). Retrieved from http://www.jyi.org/Volumes/volume11/issue2/articles/lee.html.

Delamere Vineyard

Delamere Vineyard struggles to generate a consistent net income during the company’s quest for quality wine. Richard Richardson, owner, manager, and winemaker is concerned about the long term future of Delamere Vineyard. GOALS/OBJECTIVES: Develop the highest quality of Wine Richardson has been known for developing great wine and is constantly looking for ways to improve the overall quality. In 1994, customers even stated that his Reserve Pinot Noir was amazing and far superior to their competition.Richardson currently believes in three potential improvements exist and I have outlined his potential projects (highlight below). Option 1: Prevent Excessive Oxidation (Determine optimum SO2, level) a. )Potential Benefit: Prevent oxidation; improve the consistency and â€Å"fruitiness† b. )Risk: Decrease complexity c. ) Capital Expenditure: Zero dollars d. )Production: 10%-30% scrap This option would allow Richardson to produce a consistent wine on a year to year basis. Wine t hat uses SO2 will still command a high price and sell very well on the market. Less risk can be associated with this method as well.On the downside, by producing wine using SO2 you tend to reduce the individual character of the wine. Initially Richardson will risk the chance of losing some of his harvests; given Richardson previous chemistry back ground, he should be able to develop a formula faster than others. Option 2: Deepen Red Wine Color (Implement Rotofermenter) a. )Potential Benefit: Improve customer reception; 10% price increase b. )Risk: Altered taste c. ) Capital Expenditure: Rotofermenter $30,000 d. )Production: 10% Richardson has stated that customer’s traveling to his region and surrounding markets prefer wine with darker color. By using the rotofermenter,Richardson will be able to create a darker wine, which he believes will increase his retail by up to 10%. Based on Richardson’s revenue from 1997 this method would generate an additional $24,391. 80 in s ales. This option does raise the risk of potential oxidation, which in the past has plagued Richardson. The rotofermenter also has a chance of altering the taste the wine. The cost for introducing the rotofermenter is $30,000. Option 3: Optimum Fermentation Mix (Whole bunch; Destem: Full Crush) a. )Potential Benefit: Greater complexity, â€Å"character† b. )Risk: Customers may reject c. ) Capital Expenditure: New fermentation tank . )Production: 20%-40% This method has the potential to produce amazing wine that could sell at a much higher retail. The final product will not be similar to Richardson’s competition base and could potentially give him the edge in pinot noir sales; adding complexity to ever bottle. However, the taste and quality will vary from barrel to barrel. Lots of risks are associated with this process. This method would require that the grapes are handpicked and also smashed by feet which would increase labor costs. Consistency would be the largest pro blem and could potentially lead to decreased customer satisfaction.Close to 88% of Delamere’s customer base tends to purchase’s wine based on consistency and price, rather than the complexity and character. Delamere's current customer base is comprised of 58% cellar door purchases, 37% wholesale purchases and 4% to Mail order purchases. The chart below outlines the percentages of business for Delamere Vineyard. Delamere Vineyard % of sales 1997 Delamere Pinot NoirReserve Pinot NoirDry RedChardonnay Dollars$179,424. 00$32,671. 00$31,823. 00$36,118. 00$280,036. 00 Avg. $ per bottle12. 7516. 85810. 2 Bottles Sold 1407219393978354123530 % of Business64. 7%11. 67%11. 36%12. 90% Delamere Vineyard does have small percentage of his customer’s that prefer the complexity and unusual character of Richardson’s Reserve label. However, this particular customer accounts for merely 12% of their total wine business. During Richardson’s 12 years of winemaking the sp ecter of oxidation has reared its ugly head several times. In 1993, Richardson lost his entire vintage stock of chardonnay and in 1994 his pinot noir which was considered by many as his best but was criticized by Judge James Halliday as â€Å"prematurely aged†, indicative of oxidation.Some of Delamere’s customers have recently commented about a lack of consistency with Richardson’s wine. Below is a comment from one of Delamere’s wholesaler’s. â€Å"Richard, I’m worried about this year’s pinot. It’s very different to last year’s. What are you doing different? I’m worried that if I sell this to restaurants that took last year’s they’re going to be surprised, and perhaps disappointed† –Wholesaler, commenting on the 1994 whole-bunch reserve Pinot Noir. — Generate a consistent Income Over the course of 8 years, Delamere Vineyard has struggled to produce a consistent net income.As seen in the graph below, Delamere Vineyard’s net income was as low as -$41,124 in 1993, and as high as $70,218 in 1997. The lack of consistency makes it very hard for any business owner or manager to manage their business. Richardson has stated that wine making has its peaks and valleys and that your goal as a wine maker is to minimize the valleys and capitalize on the peaks. As you take a closer look at the graph, you will notice that that Delamere’s income never really spikes during its so called peaks and plummets during its so called valleys.What is most concerning is Richardson’s inability to capitalize on what many have stated as being his best Pinot Noir wine in 1994. Following this harvest Richardson produced good profits, but not records numbers. Profitability has not been a focal point of Richardson business in previous years. However, it should be something Richardson looks to improve given the statistics above. Relaying on the peaks of Delamere is like h oping one gets lucky. Expand current operations: Option 1: Plant more grapes Richardson is currently only using up 8. 1 acres of the available 21. 3 acres, which accounts for only 38% of his land suitable for vineyards.Below is an example of how much Richardson could increase production by merely doubling his operations. 1997 Delamere Vineyard Production pinot noir chardonnaytotal Estimated production Acres of vines currently planted6. 91. 28. 116. 2 Yield per acre (Tonnes)3. 363. 366. 7213. 44 Liters of wine produced16. 2682,9052921. 2685842. 536 Casks (barrels)721385170 Evaporation and scrap (liters)97617411502300 % of scrap0 Total Liters wine (net)15,29227311802336046 Cases169930320024004 Bottles 20,38936412403048060 Library and Owners Use4001005001000 % of grape type0 Total Bottles (net)19,98935412353047060Option 2: Expand the Cellar Door Sales As stated above, Richardson is currently using 38% of his 21. 3 acres. The â€Å"Cellar Door† has become a unique experience for many of Richardson’s customers and also been a great source of revenue—roughly 58 % of Richardson business. The vast majority of the Cellar Door customer’s our tourist to the Tasmania region and Richardson should consider adding lodging accommodations for these guests. Richardson could possible encompass one nights lodging, wine seminar, and a case of wine. The obvious downsides would be the building cost and also additional employee help.Hire Additional Help: Add an additional employee that oversees the daily operations of the vineyard. This would be an added expense, but it will give Richardson the ability to focus on perfecting the wine making process. This will also help aid in future growth of the vineyard. Recommendation Given the fact that it will take time for planted grapes to harvests, I’ve broke down my recommendations based on years of operation. Year 1 In year one I’m recommending that Richardson start adding SO2 to his wine. Given Ric hardson’s chemistry background this should be relatively easy to implement.This change can be completed with very little start up cost and will help produce a consistent wine on a yearly basis; improving the overall quality of Richardson’s wine. The new wine consistency will pay dividends with Delamere’s wholesale customers—which accounts for 38% of his yearly business—where consistency has been critical. The addition of S02 has been instituted by other vineyards already and has been received well throughout the market place. Over/under oxidation will also not be as prevalent as in the previous years and should allow Richardson to increase the retail on his wine, increasing his gross margin.Richardson will need to research his competitors pricing to see how big of an increase is justified. I’m also recommending that you plant an additional 8. 1 acres of grapes. Given the fact that nearly 62% of your vineyard lays vacant, you will more than d ouble your GMROI in future years to come. Year 3 Once the newly planted crop is ready for harvest I’m suggesting that Richardson hire an additional employee that can manage your daily operations of the vineyard. It is during this time that I’m suggesting that Richardson also consider pursuing optimum fermentation.This would require the purchase of a fermentation tank but would allow Richardson to express his creativity and focus on the overall quality/complexity of your pinot noir. I recommended that Richardson only devote 4 acres of his vineyard to this method given the risk associated with this practice which I have highlighted above. Year 8 The last improvement is one that will have to be based on the over success of the other improvements mentioned above. By this time Richardson should have a grasp on whole bunch fermentation and mastered the art of adding SO2 to his wine.Richardson will have created a successful vineyard and more likely will be looking for other w ays to improve creativity of his vineyard. It is at this time I that I suggest Richardson look into developing the remaining 5. 1 acres into a bed and breakfast lodge. More than 50% of his business already comes from cellar door customers that are visiting the Tasmania region. This could become a popular venue for tourists interested in wine making, wine tasting events, weddings, and other special events. The initial cost of this recommendation would be extremely high; however, it has the potential to increase sales dramatically.

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buy custom Health Insurance Portability and Accountability Act Rules essay

buy custom Health Insurance Portability and Accountability Act Rules essay Privacy rules are rules that bring the standards of the nation to protect the individuals against medical records and personal health information that apply to health plans. It also protects them from those who provide health care in clearing houses and to the electronically provided heath care. They are essential in keeping the secret of individual health information away from the public, giving the terms and conditions to use and the dissemination of such information without permission from the owner. They also give the patient the mandate over the health information and the right to obtain and acquire a copy of health record and even ask for correction if any. Security rules establishes the nation standards that protects the individuals from electronically personal health information that is created, acquired, utilized or that is protected by a covered entity. The rule mainly aims at protecting the electronic preserved health information and the federal agencies which are covered entities under the health insurance portability and accountability act which must comply with the security rule that aims at protecting the secrecy, integrity and availability of electronic protected health information. The rule must ensure the secrecy, integrity and availability of EPHI which creates, obtains, trnsmits and protects against any reasonable anticipated uses or dissemination of such information, which is not in agreement with the privacy rule. Standardized transaction code set rules are regulation that are established by the expertise and are supposed to be followed when the rules and orders are being made. They act as a guide line to the formation of the actual rules. Health information management services information is obtained from the department of health and human services. This information is necessary in the implementation of health insurance portability and accountability act strategy. As shown in the context in a technological view point James is responsible for making sure that, all the health information is accurately gathered, kept and, protected. The information obtained from this department is useful to the chief information officer in decision making, which is of importance to the organization and the members of the staff. Clinical nursing services information is obtained from the department of health and human services. It gives data which are essential in the decision making of the department and the orga nization at large. The information is gathered from the various activities, which takes place within and outside the clinics. Credit department is in the health and human services department and it is used to record all the transactions, which takes place in that department. The information recorded is used to analyze the performance of the organization which is useful to the members of the staff in decision making. Treatment is the provision, staffing or management of health care services and any similar services among those who provide health care or a third party with a health care provider consulting between the health care providers regarding a client or the referral of the client from one health care provider to another. Payments are the various activities which provide health care services to obtain payments or to compensate for their services and for those of health plan to receive premiums for the fulfillment of their coverage responsibilities and give benefits under the plan. Operations refer to the administration, finance, legal and quality improvement activities that of an entity which is covered, that are necessary to operate the business and to support the main functions of treatment and payments. The chief compliance officer is correct because the information follows the health insurance portability and accountability act which gives the directions on how to set the rules and on how they should be regulated. Buy custom Health Insurance Portability and Accountability Act Rules essay

McCulloch v. Maryland, 1819

McCulloch v. Maryland, 1819 The court case known as McCulloch v. Maryland of March 6, 1819, was a seminal Supreme Court Case that affirmed the right of implied powers, that there were powers that the federal government had that were not specifically mentioned in the Constitution, but were implied by it. In addition, the Supreme Court found that states are not allowed to make laws that would interfere with congressional laws that are allowed by the Constitution.   Fast Facts: McCulloch v. Maryland Case Argued: February 23- March 3, 1819Decision Issued:  March 6, 1819Petitioner: James W. McCulloch,Respondent: State of MarylandKey Questions: Did Congress have the authority to charter the bank, and by imposing taxes on the bank, was the State of Maryland acting outside of the Constitution?Unanimous Decision: Justices Marshall, Washington, Johnson, Livingston, Duvall, and StoryRuling: The Court held that Congress had the power to incorporate a bank and that the State of Maryland could not tax instruments of the national government employed in the execution of constitutional powers. Background In April 1816, Congress created a law that allowed for the creation of the Second Bank of the United States. In 1817, a branch of this national bank was opened in Baltimore, Maryland. The state along with many others questioned whether the national government had the authority to create such a bank within the states boundaries.  The state of Maryland had a desire to limit the  powers of the federal government. The General Assembly of Maryland passed a law on February 11, 1818, which placed a  tax on all notes the originated with banks chartered outside of the state. According to the act, ...it shall not be lawful for the said branch, office of discount and deposit, or office of pay and receipt to issue notes, in any manner, of any other denomination than five, ten, twenty, fifty, one hundred, five hundred, and one thousand dollars, and no note shall be issued except upon stamped paper. This stamped paper included the tax for each denomination. In addition, the Act said that the President, cashier, each of the directors and officers .... offending against the provisions aforesaid shall forfeit a sum of $500 for each and every offense....   The Second Bank of the United States, a federal entity, was really the intended target of this attack. James McCulloch, the head cashier of the Baltimore branch of the bank, refused to pay the tax. A lawsuit was filed against the State of Maryland by John James, and Daniel Webster signed on to lead the defense. The state lost the original case and it was sent to the Maryland Court of Appeals. Supreme Court The Maryland Court of Appeals held that since the US Constitution did not specifically allow the federal government to create banks, then it was not unconstitutional. The court case then went before the  Supreme Court. In 1819, the Supreme Court was headed by Chief Justice John Marshall. The court decided that the Second Bank of the United States was necessary and proper for the federal government to exercise its duties.   Therefore, the US National Bank was a constitutional entity, and the state of Maryland could not tax its activities. In addition, Marshall also looked at whether states retained sovereignty. The argument was made that since it was the people and not the states who ratified the Constitution, state sovereignty was not damaged by the finding of this case.   Significance This landmark case declared that the United States government had implied powers as well as those specifically listed in the Constitution. As long as what is passed is not forbidden by the Constitution, it is allowed if it helps the federal government fulfill its powers as stated in the Constitution. The decision provided the avenue for the federal government to expand or evolve its powers to meet an ever-changing world.

Cover Letter Tips for Receptionists

Cover Letter Tips for Receptionists The job search experts at Best-Job-Interview.com have developed this cover letter template for receptionists looking for their next opportunity. My annotations are italicized after each paragraph- feel free to update and adapt to your experiences or reword to reflect your own voice! The more personalized your letter is for its intended recipient, the better.Your Name   Your Address   Your Contact details (phone and email)  Even if youre submitting online, if youre given the opportunity to upload a document, format it like you would a letter. If youre using an email to send your cover letter, include your name and contact information in your email signature instead.DateMs Mary Stevens   Hiring Manager   ABC Company   15 South Parkway   Long Island, NY 11551  Again, an online submission process can throw a wrench in here, but if there are any contact details for the HR department online, call in and just ask the receptionist who will be reviewing the materials so you ca n personalize your letter. It looks much better than just To whom it may concern and shows youre willing to take initiative and go above and beyond, before youve even landed the interview.Dear Ms. Stevens:Err on the side of Ms over Miss or Mrs. If the gender of a name is ambiguous, the safest option is to use the full name, i.e. Dear Alex StevensYour job posting for a receptionist at ABC company caught my attention immediately as my skills and experience are a close match to your requirements for this position. Im a longtime fan of ABCs work with companies like Generics Inc. Thank you for your consideration of my application and the enclosed resume.   Notice the specificity of the opening paragraph- Jane names the company and indicates she has some knowledge of its work. If shed encountered the post on a specific job site, or even better, received a word-of-mouth referral, she could have mentioned that here as well. Dont try to fake it- actually research any company youre applying to, and try to find some positive mention of them in the news to enrich your letter.I have three years work experience as a receptionist in a large organization where I was responsible for handling all calls and visitors in addition to providing extensive organizational and administrative support. I am a self-directed and independent worker who has taken the initiative to learn as much as possible about the company I work for in order to become a valuable information resource.  Obviously this is a generic version of a skill summary- you would want to name your previous employer and possibly mention a specific example of something youd learned about or a project you initiated. Whats noteworthy is that its not just a repetition of a resume bullet point, but a broader summary.Organizational and planning skills are among my particular strengths. I have developed a number of processes to manage my varied responsibilities tasks and make sure I meet the demands of a fast-paced work envi ronment. I utilize technology to assist me wherever possible and have a good working knowledge of a number of computer applications including MS Office.   This is fairly vague also- an experienced receptionist should be able to refer to specific processes or scheduling and project management programs. If this crossed my consultant desk, I would suggest Jane use more positive language like Im comfortable with content management systems and learning proprietary software on the job.My strong communication skills and outgoing, energetic personality ensure that I provide first-rate customer service to both clients and colleagues. I thoroughly enjoy dealing with a wide variety of people and take pride in being the face of an organization or the first point of contact over the phone.This is where a close reading of the job description comes in handy- highlight aspects of your personality, as Jane does, that will conform to the demands of the job. I like that Jane mentions both outside cl ients and her colleagues, since a good receptionist has to be able to get along with everybody.ABC Company enjoys an excellent reputation and I am confident that I would be an asset to your company. I look forward to the opportunity to discuss my abilities in more depth and am available for an interview at your earliest convenience. Please contact me via phone or email to arrange a convenient time for us to meet. Thank you for your time and consideration and I hope to speak with you soon.End with a note about the company youre applying to, and indicate your availability for an interview. Make sure it doesnt sound like a demand or a hostage negotiation, but is breezy and polite!Sincerely,Jane JobseekerAug 10, Job-Winning Receptionist Cover LetterRead More at Best-job-interview

Evolution Lab Report Example | Topics and Well Written Essays - 500 words

Evolution - Lab Report Example The major tool used in this biological experiment was a specially programmed computer application (automated) that enables adjustment of variables from default figures and when run, accurate results on the changes that has occurred in the biological structures of living organisms were shown. These results are therefore used to justify the hypothesis. In the first experiment, when the independent variable (precipitation) is adjusted to higher levels, the birds evolve smaller beaks. This is because when precipitation is high then the seeds become softer and the birds slowly adjust to the changes of nature until the fully adapt. On the other hand when precipitation is low, the seeds become harder and the need for additional force to crack the seeds arise and based similar principle; the birds evolve stronger and larger beaks over time (Sober, 2008). This adjustment may not favor some birds as the adaptation and evolution process is gradual and therefore may lead to death of individuals that are unable to adjust effectively to the changes of nature. Natural selection can influence variation of a trait in a population in three major forms namely; diversifying, directional and stabilizing forms (Sober, 2008). In the second experiment, it is clearly evident that changes in the environmental conditions favors the individuals with specific phenotypes. When important parameters that influence natural selection such as precipitation is manipulated (adjusted to 50cm/year and 0cm/year on Wallace Island and Darwin Island respectively), it is noted with great significance that only a few individuals are able to survive and continue reproducing in an environment with low precipitation. This is because of the variation in biological and environmental factors that are very significant for natural selection. Therefore for a period of 300 years, these changes will influence the evolution of Finch beaks and in turn affect their population. This fact can be justified by the graphs

Information Security Access Control Methods Assignment

Information Security Access Control Methods - Assignment Example Passwords are granted to the end user for accessing their accounts. User access can be managed locally or by policies defined by the organization. It is a method of strengthening the network security by limiting the accessibility of network resources to communicating devices that fulfill with a proposed security policy. Network Access Control method restricts the end users from accessing particular resources within the network. (Helfrich, Frahim, Santos, & White, 2007, p. 396-397) A well planned network access control strategy includes anti-threat applications like anti-viruses, intrusion detection systems, spywares prevention programs, as well as access control lists (ACLs). It also shapes the individual access to particular resources, once connected. Access control for an OS establishes the process of implementing access level policies of the system’s resources satisfying the security policies of integrity, availability, and confidentiality. This procedure authorizes processes/users to carry out certain operation different resources of the operating system. It is method of securing information systems. It converts the information to some language that is only understandable by the user for whom it was ciphered. This process starts by ciphering the plain text to a cipher-text for scrambling the information into some cryptographic language. (Peltier, Peltier, & Blackley, 2005)The individual who performs the encryption and decryption is named as

The Impact of ASEAN Free Trade Agreement on Malaysian Automotive Dissertation

The Impact of ASEAN Free Trade Agreement on Malaysian Automotive Industry - Dissertation Example verview of Research Methods 3 1.6 Research Significance 4 1.7 Dissertation 4 1.8 Summary 5 Chapter 2: Literature Review 6 2.1 Introduction 6 2.2 Overview of Malaysian Automotive Industry 6 2.3 ASEAN Free Trade Area 9 2.4 Malaysian Governments’ Reaction to AFTA 10 2.5 Impact of AFTA on Industry 13 Chapter 3: Research Methodology 18 3.1 Introduction 18 3.2 Research Approach 18 3.3 Research Methods 19 3.4 Research Design 20 3.4.1 Sample 20 3.4.2 Data Collection Method 21 3.4.3 Data Collection Instrument 22 3.4.4 Data Analysis 22 3.5 Ethical Considerations 23 3.6 Summary 23 Chapter 4: Findings and Results 24 4.1 Introduction 24 4.2 Section A: Findings from the Customer Interviews 24 4.2.1 Customers’ Perception of Impact of AFTA 24 4.2.2 Customers’ Perception of the fate of PROTON and PERDUA with AFTA 25 4.2.3 Perception of Governments’ Policies 27 4.2.4 Customers’ Preference: Imported vs. Indigenous 27 4.2.5 Customers’ Perception of Problems as a direct result of AFTA 28 4.2.6 Customers’ Perception of Advantages of AFTA 29 4.2.7 Customers’ Perception of the Problems Related to Increase in Traffic Post AFTA.29 4.2.8 Customers’ Perception of Public Transport 30 4.2.9 Customers’ Perception of Selling Indigenous Cars to buy Imported Cars 30 4.2.10 Customers’ Perception of Need to Support Local Manufacturers 30 4.2.11 Customers’ Opinion of Changes that PROTON and PERODUA should undergo to meet the challenges of AFTA 31 4.3 Section B: Financial Analysis of PROTON and PERODUA 31 4.3.1 Ratio Analysis - PROTON HOLDINGS BHD 31 4.3.2 Ratio Analysis - DAIHATSU 35 Chapter 5: Discussion and Analysis 39 5.1 Introduction 39 5.2 Malaysian Government’s Approach to Combat impacts of AFTA 39 5.3 Perception of Malaysian consumers on Policies of Malaysian Government 43...The industry has shown a 20% growth in output in 2010 and appears to be heading towards an era of continuous growth in the futur e (Dinne et al, 2010). While Malaysia started as a country where International brands of cars were initially assembled, the progressive policies of the government have now made the country a manufacturer of world class vehicles. Perusahaan AutomobilNasional (PROTON) and Perusahaan OtomobilKeduaSdn. Bhd (PERODUA) now produce automobiles that dominate the Malaysian market. This has been made possible by enacting a series of protectionist policies like the requirement of local content, local labour, local partnership on the foreign companies that wanted to open their assembly plants in Malaysia. In addition, the government has proactively invested time and resources in boosting the two national automotive organizations - PROTON and PERODUA. As a result of the governmental policies, PROTON and PERODUA sell 90% of all domestic requirements while the two companies also export a large number of units worldwide (Business-in-Asia.com (n.d). However, with the implementation of Asian Free Trad e Area (AFTA) in the year 2005, the Malaysian automotive industry faced new challenges from neighbouring countries like Thailand and China, in terms of the quality and pricing and availability of imported cars in the market (Gabilaia, 2001).

Mktg Essay Example | Topics and Well Written Essays - 250 words - 5

Mktg - Essay Example When the correct market for Pradaxa has been identified, the product would be easily sold. In case, the company is attracting few people who are in dire need of Pradaxa, it is important to search for a remedy by focusing on large and correct market segments. In addition, it is good to have a clear understanding of the target market who in this case are patients with atrial fibrillation. The more the market is understood, there is high possibility of developing trust in customers who purchase the product. In addition, it is important to identify the age of your market so as to avoid targeting wrong age (Moehlman 46). For instance, Pradaxa product would target people aged sixty and above because most people of this age in U.S suffer from atrial fibrillation. The company should make an assessment to establish if the customers are satisfied with the product, if not, then the company should attempt to find a solution to their needs by improving on its product. Another important aspect of target market is that the company needs to look at the available competition. By doing this, Pradaxa product should be supplied to under-served markets. It is prudent to assess the strength and weakness of your competitors and try to find mechanism that can be different from them. Pradaxa has for long time faced competition from Warfarin. There is need to utilize opportunities such new uses in surgery patients and eliminate threats such as bad publicity dealing with side effects so as to compete favorable with Warfarin and attract more

Entrance Strategies Essay Example | Topics and Well Written Essays - 750 words

Entrance Strategies - Essay Example is reason, it is assumed that the license has benefits to both members of the agreement; otherwise, they would not be partisan to the license in the first place. In the corporate scene, the licensor usually receives royalty fees due to the permission granted to the licensee. Unlike in the past, an increased number in licensing agreements has been witnessed, especially in the corporate sector. Although different licenses contain different attributes with respect to the nature of the transaction, it is possible to tell an attractive license from one that is not attractive. Acknowledgement of these characteristics is a sure way of ensuring insulation from anticipated loss because of an unfavorable license agreement. Licensing is unattractive to a firm if: Previous knowledge describes competitive advantage as the ability of a firm to overpower its rivals. It is the condition experienced when a firm it is able to combine elements of its production process in an effective way that outperforms the rivals (John, 1996). Propriety technology is a specific process or item that tends to posses some great deal of benefit to the individual owning it. In actual sense, it may involve a special combination mix whose manipulation yields very rewarding results to the owner. As such, the ability to produce a proprietary technology individually yields an asset that can be quantified in terms of value. It is to be noted that, the proprietary technology is transferrable from one individual to another through sale for instance or even licensing making the tool volatile. This is made possible thanks to the ability to separate the technology from the individual who produced it. Therefore the source of the technology reaps benefits inform of royalties in th e case of licensing it out. Now, based on the adequate background information shared, it is clear that proprietary technology is highly valuable given the high regards associated with it. However, the volatility attribute of the same

Five Entries in an Activist Diary Assignment Example | Topics and Well Written Essays - 500 words

Five Entries in an Activist Diary - Assignment Example The flamenco flash mobs in Spain became too successful that such protests occurred similarly in London and in the St Georg’s Square. The flamenco flash mobs protest in Spain was being facilitated by central bank’s crisis (Daph, 2013; pg. 01). Other political art forms that facilitated the protest is then flight in Spain including the Barcelona’s hands project that involved the use of the plastics that were scattered across the city. This protect is considered democratic since the relevant authorities never interfered with the protest that is addressing the current concerns of the common people. It should be noted that is protest was facilitated by marginalization and economic crisis in Spain. The Tahrir Square Like any protest in Egypt, the Tahrir square protest was an aftermath of the 2011 protest of anti Hosni Mubarak’s leadership. The protestors in this riot were Muslims who demonstrated in the commemoration of forty-two protestors who were killed in op posing the government that was in power after the downfall of Mubarak (El Deeb and Gabriel, 2013; Pg. 01). Notably, this is an activism democratic protest since it was facilitated by the fall of other protestors. The protestors felt that some people had betrayed the spirit of their 2011 revolution; thus, they wanted that spirit honored.

Entrance Strategies Essay Example | Topics and Well Written Essays - 750 words

Entrance Strategies - Essay Example is reason, it is assumed that the license has benefits to both members of the agreement; otherwise, they would not be partisan to the license in the first place. In the corporate scene, the licensor usually receives royalty fees due to the permission granted to the licensee. Unlike in the past, an increased number in licensing agreements has been witnessed, especially in the corporate sector. Although different licenses contain different attributes with respect to the nature of the transaction, it is possible to tell an attractive license from one that is not attractive. Acknowledgement of these characteristics is a sure way of ensuring insulation from anticipated loss because of an unfavorable license agreement. Licensing is unattractive to a firm if: Previous knowledge describes competitive advantage as the ability of a firm to overpower its rivals. It is the condition experienced when a firm it is able to combine elements of its production process in an effective way that outperforms the rivals (John, 1996). Propriety technology is a specific process or item that tends to posses some great deal of benefit to the individual owning it. In actual sense, it may involve a special combination mix whose manipulation yields very rewarding results to the owner. As such, the ability to produce a proprietary technology individually yields an asset that can be quantified in terms of value. It is to be noted that, the proprietary technology is transferrable from one individual to another through sale for instance or even licensing making the tool volatile. This is made possible thanks to the ability to separate the technology from the individual who produced it. Therefore the source of the technology reaps benefits inform of royalties in th e case of licensing it out. Now, based on the adequate background information shared, it is clear that proprietary technology is highly valuable given the high regards associated with it. However, the volatility attribute of the same

Demerits of Advertising Essay Example for Free

Demerits of Advertising Essay Advertising is a form of communication used to encourage or persuade an audience (viewers, readers or listeners) to continue or take some new action. Most commonly, the desired result is to drive consumer behavior with respect to a commercial offering, although political and ideological advertising is also common. The purpose of advertising may also be to reassure employees or shareholders that a company is viable or successful. Advertising messages are usually paid for by sponsors and viewed via various traditional media; including mass media such as newspaper, magazines, television commercial, radio advertisement, outdoor advertising or direct mail; or new media such as websites and text messagesModern advertising developed with the rise of mass production in the late 19th and early 20th centuries. Type Demerits1 Demerits of Advertising (Objections) Various objections against it may be listed as follows: 1. Economic Objections a) Advertising is not productive. It is true that it does not produce any tangible goods. It is said to involve wasteful expenditure. b) It forces people to desire and buy goods, which, in fact, are not within their means.  c) It increases the cost of goods. Advertising charges are included in the price, which the consumer has to pay. d) Advertising results in monopoly. The consumer becomes a slave to a particular brand. 2. Social Objections a) Most of the advertisements contain tall claims and the consumers do not enjoy the benefits advertisement in full. They are shortlived only. b) The press is influenced by the advertisers because they provide major revenue for the existence of newspapers. 3. Ethical Objections a) Advertising appeals make people to use such articles, which may affect their health. For example alcoholic drinks and cigarettes. b) People with less purchasing power cannot afford to buy articles even though advertisements create a strong need in them. Thus a section of society remains discontented. Whatever may be said against advertising, it is increasingly used almost in every branch of business to promote sales. It is not merely a means of sales promotion but today it has become a science equivalent to any other social science. Type Demerits 2 These are the disadvantages of advertising: Increases the cost: It increases the cost of goods. The cost of the advertisement is included in the price and is ultimately borne by the customers. Misleads the public: It misleads the public by giving false statements about the product. (It may be true in some cases but majority of advertisers know the value of honest statements.) Creates a dissatisfaction: It creates tastes and desires for some people whose income may not allow them to buy. Such people feel dissatisfied. Creates a monopoly: It increases monopolistic trend. Due to advertisement some manufacturers create monopoly in industry and thus reduce healthy competition. It becomes difficult for new firms to enter the field. Creates the confusion: It creates the possibility of wrong purchases. Being impressed by the advertisement, in some cases, a person is not able to purchase the commodity, which he actually wants to purchase. Encourages luxury: This encourages luxury. Mostly the commodities related to comforts and luxuries are advertised, for example, cigarettes, cosmetic goods and etc. due to advertisement of cigarettes several persons start smoking cigarettes, which becomes habit. Reduces cleanliness: It reduces cleanliness. Large number of posters and writings on the walls are used for advertisement. This makes the roads and the walls of the houses look dirty. Thus, it reduces the natural beauty. Causes wastage: It is a cause of wastage of natural resources. As a results of advertisement, style and fashion change quickly. It makes the goods out of fashion.

Effect of Oxidative Stress in Fertile and Non Fertile Women

Effect of Oxidative Stress in Fertile and Non Fertile Women 3. MATERIAL AND METHODS The materials and methods used in the study entitled â€Å"Comparative study of effect of oxidative stress in fertile and non fertile women† was carried out in the Faculty of Health and Medical Sciences, SHIATS, Allahabad. The detail of experimental techniques employed is as follows: MATERIALS STUDY AREA The blood sample of infertile and fertile selected married females having child bearing age (25-35yrs) without any metabolic disorder from different gynecologist clinical hospitals and infertility centers of Allahabad. COLLECTION OF SAMPLE AND SITE OF EXPERIMENT: The present study was carried out by collecting venous blood sample (5ml) of fertile and non fertile selected married females in Allahabad. Group-I 250 normal healthy fertile women without any metabolic disorder, Group-II 250 infertile female without any metabolic disorder. All the subject of the two groups were between the age group 25-35 yrs. 3.2 Glassware: All the glassware used were washed properly with detergent and rinsed with distill water and autoclaved prior to use. Fig.3.1: Flow chart for fertile and infertile females Instrumentation: The following instruments were used during the course of study Autoclave Centrifuge Balance (Remi) Cooling centrifuge (remi C-28) Hot air oven (tempo) Homogenizer Incubator Micropipette tips (100 and 1000  µl) pH meter Spectrophotometer Weighing balance Centrifuge Colorimeter Routine Investigation The routine investigation of the subject include BMI and weight and history which was taken by asking the subjects to fill a from including 9their approval to be a part of the study. 3.5 Routine biochemical analysis:- All of the blood sample were analyzed for 3.5.1 Evaluation of Routine biochemical Parmeters:- Hb : By Sahli (acid hematin) method. Blood Sugar :By GOD/POD method Glycosylated Hb : By Cation method Serum Protein:Biuret method Serum lipid profile Serum Total Cholesterol : By Autopack Kit Method Serum Triglyceride : By Autopack Kit Method Serum HDL Cholesterol : By Autopack Kit Method Serum LDL cholesterol : Friedwald method Serum VLDL cholesterol : Friedwald method 3.5.2 Thyroid Profile:- Serum T3 :ELISA Method Serum T4 :ELISA Method Serum TSH :ELISA Method 3.5.3 Female Reproductive hormones: Serum Estrogen: :ELISA Method Serum Progesteron: :ELISA Method Serum follicle stimulating hormone (FSH) :ELISA Method 3.5.4 Oxidative Stress marker:- Melondialdehyde (MDA): By the santos (1978)method 3.5.5 Antoioxidant level:- Catalase: Brannan (1981) method Ceruloplasmin: By Spectrophotometric method Superoxide dimutase (SOD): By Mishra and Fridovich (1972)Method Estimation protocol of routine biochemical protocol : The body weight and height was calculated manually with the help of weight balance and length scale respectively. Body mass index (BMI): The Body mass index was calculated when body weight is divided by the square of height. 3.5.1 Estimation of Hemoglobin: Hemoglobin reacts with0.1N hydrochloric acid and forms a brown colour complex called hematin.The resulting color after dilution is compared with standard brown glass reference blocks of a sahli hemoglobinometer. Reagent: N hydrochloric acid. Distilled water. Procedure:- By using pasture pipette add 0.1N hydrochloric acid in the tube up to the mark 20 Add 20ul blood to the tube. Leave the solution for 10 mins. Dilute the solution by adding few drops of distill water at a time till the color matches with the glass plate in the comparator. Read the reading. Normal value: In female: 12-14mg/dl In males: 14-16 mg/dl 3.5.2 Estimation of Blood Glucose: Estimation of blood glucose was carried out by using commercial available GOD-POD glucose reagent kit (Autospan, Span diagnostic limited, Surat, India). Glucose oxidase (GOD) oxidizes glucose to gluconic acid and hydrogen peroxide. In presence of enzyme peroxidase, released H2O2 is coupled with phenol and 4-aminoanrttipyrine (4-AAP) to form coloured quinoneimine dye. The absorbance of dye is directed proportional to glucose concentration in the sample (Kaplan, 1984) Glucose + O2 + H2O Gluconic acid+ H2 O2 H2O2 + phenol + 4-AAP Qinoneimine Dye + H2O Reagents: 1) Glucose reagent Phosphate buffer Glucose Oxidase Peroxidase 4-amino antipyrine. 2) Glucose diluents 3) Glucose standard Procedure:- Preparation of working Solution: All the reagent are ready -to-use. Pipette into test tube marked Blank Standard Test Serum/plasma 20  µl Cholesterol Standard 20  µl Mix well and incubate at 37 C for 10 minutes at room temp Distilled water 1500  µl 1500  µl 1500  µl The absorbance of the test was taken after standard at 490-550 nm. Calculation: Serum/plasma glucose concentration (mg/dl) = Absorbance of test x 100(Conc. of Std) Absorbance of Std Normal Range: Fasting glucose: 65-110mg/dlPost Prandial: Upto140 mg/dl. 3.5.3 Estimation of Glycosylated hemoglobin (HbA1C) The Glycosylated hemoglobin was estimated by (ion exchange resin method) commercially available kit (ERBA Diagnostic Mannheim, Transasisa Bio-Medicals limited, Solan India).A hemolysed preparation of the whole blood is mixed continuously for 5 min with a weak binding cation resin. During this time, HbAo binds to the resin. After the mixing period, a filter is used to separate the supernatant containing the Glycohaemoglobin from resin (Trivelli et al 1971) Hemolysed whole+ Cation exchange resin Fast Fraction Blood separation ( HbA1a,HbA1c,HbA1c) Reagents: Glycohaemoglobin Ion Exchange Resin Reagent Cation-Exchange Resin (8mg/ml) Glycohaemoglobin Lysing Reagent Lysing Agent (10 m M) Glycohaemoglobin Calibrator Calibrator (10%) PROCEDURE: The reaction mixture contained 500 µL Lysing Reagent and 100  µL whole blood and another tube 500  µL Lysing Reagent and 100  µL Calibrator mix and allow it to stand for 5 minutes till lysis is complete. Add 0.1 ml of the hemolysate from step-1 into the approximately marked Ion-Exchange Resin tubes. Close the cap and allow continuous gentle mixing for 5 minutes. Allow the resin to settle to assay temperature for 5 minutes. Position the resin separator in the tube and push down the separators until the resin is firmly packed. Read the absorbance of each tube at 415 nm against deionised water bank. For the fraction of hemoglobin add 20  µL sample hemolysate in 5.0 ml deionised water in calibrator 20  µL Calibrator Hemolysate in 5.0 ml deionised water, mix well and read the absorbance of calibrator and sample at 415 nm against deionised water. Normal Range: 6- 8.3 % Hb 3.5.4 Estimation of Serum Protein: The protein was estimated (Biuret method, End method) by commercially available kit (ERBA diagnostic Mannheim, Transasia Bio-Medicals Limited, Solan, India). The peptide bonds of protein react with copper II ion in alkaline solution to form blue violet color complex, (biuret reaction). Tartarate is added as a stabilizer whilist iodide is used to prevent auto-reduction of the alkaline cooper complex. The absorbance of color complex is proportional to protein concentration (Tietz 1986) Reagents: Total reagent Copper II sulphate Potassium Sodium Tartarate Potassium Iodide Sodium Hydroxide Protein standard Procedure:- Preparation of working Solution: All the reagents are ready -to-use. Pipette into test tube marked Blank Standard Test Serum/plasma 20  µl Protein Standard 20  µl Total protein reagent 1000  µl 1000  µl 1000  µl The absorbance of the test was taken after standard at 546 nm. Calculation: Serum/plasma total protein concentration (g/dl) = Absorbance of test x 6.5 Absorbance of Std Normal Range: Serum Total protein : 6.4-7.8 g/dl 3.5.5 Estimation of lipid profile: Determination of total cholesterol in serum/plasma: Method Name: CHOD-PAP method Principle: Cholesterol esters are hydrolyzed by Cholesterol Esterase (CE) to give free Cholesterol and fatty acids. In subsequent reaction , cholesterol oxidase (CHOD) oxidizes the 3-OH group of free Cholesterol to liberate cholest-4-en-3-one and Hydrogen Peroxide. In presence of Peroxidase (POD), Hydrogen Peroxide couple with 4-Amonoantipyrine (4-AAP) and phenol to produce red Quinoneimine dye . Absorbance of colored dye is measured at 505 nm and is proportional to amount of total cholesterol concentration in the sample. Procedure: Preparation of working Solution: All the reagent are ready -to-use. Pipette into test tube marked Blank Standard Test Serum/plasma 10 µl Cholesterol Standard 10  µl Cholesterol Reagent 1000  µl 1000  µl 1000  µl Mix well. Incubate at 37’c for 10 minutes or at room temperature (15-30’c) for 30 minutes. Read the absorbance of the sample Standard against blank. Calculation: Cholesterol concentration (mg/dl) = Absorbance of test x 200(Conc. of Std) Aborbance of Std Normal Range: 150-250 mg/dl. 3.5.6 Determination of HDL Cholesterol in serum/plasma: Method Name: CHOD-PAP Principle: Low density Lipoprotiens (LDL) Cholesterol, Very Low Density Lipoprotiens (VLDL) cholesterol and Chylomicron fractions are precipitated by addition of polyethylene Glycol 6000 (PEG) .After Centrifugation, the High Density Lipoprotien (HDL) Fraction in the supernatant is determined with CHOD-PAP method. Procedure: Preparation of working Solution: All the reagent are ready -to-use. STEP-I: HDL-Cholesterol separation Take 0.5 ml of serum /plasma in to a glass tube. Add 50ul precipitating reagent. Mix well; leave it for 10 min at room temperature. Centrifuge at 3000 rpm for 10 min. Take the clear supernatant for HDL-Cholesterol. STEP-II: HDL-Cholesterol Estimation. Pipette into test tube marked Blank Standard Test Supernatant form step-I _ _ 10 ul HDL-Cholesterol Standard _ 10 ul _ Cholesterol Reagent 1000 ul 1000 ul 1000 ul Mix Well. Incubate at 37’c for 5 minutes or at Room temperature (15-30 ºC) for 30 minutes.. Read the absorbance of the sample Standard against blank at 510 nm. Calculation: HDL-Cholesterol concentration (mg%)= Absorbance of test x 200(Conc. of Std) Absorbance of Std Normal Range: Men=30-60 mg%, Women= 40-70 mg%. 3.5.7 Estimation of Low Density Lipoprotein (LDL) LDL= Total Triglyceride HDL 5-HDL LDL cholesterol were obtained by calculation using the empirical relationships of (Friedwald et.al.1995) 3.5.8 Estimation of Very Low Density Lipoprotein (VLDL) VLDL =Total triglycerides/5 VLDL cholesterol were obtained by calculations using the empirical relationships of (Freidwald et.al 1995) 3.5.9 Determination of Triglyceride in serum/plasma: Method Name: GPO-TRINDER Principle: Lipoprotein lipase hydrolyses triglycerides to glycerol and free fatty acid. The glycerol formed with ATP in the presence of glycerol Kinase forms Glycerol 3 Phosphate which is oxidized by the enzyme glycerol phosphate oxidase to form hydrogen peroxide. The hydrogen peroxide further reacts with phenolic compound and 4-aminoantioyrine by the catalytic action of peroxidase to form a red coloured quinoneimine dye complex. Intensity of the colour formed is directly proportional to the amount of triglycerides present in the sample. The intensity of chromogen (Quinoneimine) formed is proportional to the Triglyceride in the sample when measured at 505nm (500-540nm). Preparation of working Solution: Allow the reagent bottle and AQUA-4 to attain room temperature .Add the amount of AQUA-4 indicated on the label to the contents of each vial. Swirl to dissolve, allow to stand for 10 min at room temperature. Procedure: STEP-II: HDL-Cholesterol Estimation. Pipette into test tube marked Blank Standard Test Working reagent 1000 ul 1000 ul 1000 ul Distill Water 10 ul _ _ Standard 10 ul Sample 10 ul Mix Well. Incubate at 37’c for 10 minutes. Read the absorbance of the sample Standard against blank at 505 nm (500-540nm) or 505/670nm on bichromic analysers against reagent blank. Calculation: Triglyceride (mg/dl) = Absorbance of test x Conc. of Std (mg/dl) Absorbance of Std Normal Range: Normal fasting levels: 25-160mg/dl. Oxidative stress marker : 3.6.1. Determination of Melon di aldehyde (MDA) in serum/plasma: Reagents required: Tricholoro acetic acid TCA Sulfuric Acid HCL Sodium sulfate N-Butanol 5-1,1,1,3,3 Tetra Ethoxypro-pane (Standard) Procedure: Malondialdehyde (MDA) Assay: Lipid peroxidation in the plasma is evaluated by the spectrophotometric method based on the reaction between MDA and Thiobituric acid (TBARS). Briefly, to 0.5 ml plasma, 2.5 of 20% tricholoro acetic acid (TCA) in 2M sodium sulfate is added. After precipitating the protein with TCA and washing with 0.05sulfuric acid. It was incubated in a boiling water bath for 30 min. After cooling, the samples are exactracted with n-butaneol and centrifuged at 3500rpm. The absorbance of samples is determined at 530nm. Calculation: TBARS (A) =10 x OD of sample/OD of control (Blank) x mg/ml protein. ) Normal Range: 0.5-2.0 nmol/ml 3.7. Estimation of enzymatic antioxidants: 3.7.1 Estimation of SOD activity in serum/plasma: Reagents required: Carbonate buffer (0.2M) Kcl (0.015 M) Epinephrine (0.025M) Preparation of the sample: Collect blood without using an anticoagulant such as heparin, citrate or EDTA. Allow blood to clot for 30 minutes at 25à ¡Ã‚ ´Ã‚ ¼C Centrifuge the blood at 2000 rpm for 15 minutes at 4à ¡Ã‚ ´Ã‚ ¼c.Pipette off the top yellow serum layer without disturbing the white Buffy layer. Procedure: 1 .The reaction mixture composed of 0.1 ml of carbonate buffer (0.2M, pH 10.2), 0.8ml KCl (0.015 M) 0.1 ml of diluted blood and water to make the final volume to 3.0 ml. 2. The reaction was started by adding 0.2 ml of epinephrine (0.025 M). 3. Change in absorbance was recorded at 480 nm at 15 sec interval for 1 min at 25à ¡Ã‚ ´Ã‚ ¼C.(UV-1800 SHIMADZU)Suitable control lacking enzyme preparation was run simultaneously.( Mishra and Fridivicl;1972). Calculation: one unit of enzyme activity is defined as the amount of enzyme causing 50% inhibition of auto oxidant of epinephrine under experimental condition. SOD Activity= Normal range: 12-16 unit/mg protein 3.7.2 Estimation of Ceruloplasmin activity in serum/plasma: At pH 5.4, ceruloplasmin catalyzes the oxidation of PPD to yield a colored product, which is believed to correspond either to Bandrowski’s base or to Wuerster’s red . The rate of formation of the colored oxidation product is proportional to the concentration of serum ceruloplasmin if a correction is made for nonenzymatic oxidation of PPD. Therefore, simultaneous assays are carried pH 5.45, which has been warmed to 37 ºC.The contents of the flask are adjusted to pH 5.45 at 37 ºC by dropwise addition of sodium hydroxide solution (1 mol/liter), and diluted to the mark with acetate buffer solution. The solution is stable for3h. Procedure (1) Into two test tubes (12 X 75 mm), labeled R (reaction) and B (blank), 2 ml of acetate buffer solution was pipetted. (2) Serum, 0.1 ml, is added to each tube. (3) Tubes R and B are placed in a water bath at 37 ºC to reach thermal equilibrium. A flask  containing buffered PPD solution is also placed in the water bath. (4) Warmed, buffered PPD solution (1 ml) is added to both tubes. The contents of the tubes are mixed, and the tubes are kept unstoppered in the water bath. The water bath is covered, to avoid exposure of the tubes to light. (5) After 5 min, 50  µl of sodium azide solutionis pipetted into tube B, and the contents are mixed. The tube is replaced in the water bath. (6) Exactly 30 min later, 50  µl of sodium azide solution is added to tube R, and the contents are mixed. (7) Samples R and B are transferred to spectrophotometer cuvette (light path, 1 cm), and absorbance is measured at 530 nm with a spectrophotometer. The color of the samples remains stable for at least 6 hrs. Calculations Ceruloplasmin (g/liter) = 0.752 (A AB), where AR is the absorbance of sample R, and AB is the absorbance of sample B. Normal range: 20-37mg/dl 3.7.3 Estimation of Catalase (CAT) activity in serum/plasma: Reagents: H2O2(1.2mM) Phosphate Buffer (pH-7.0)(0.05M) Peroxidase /potassium dichromate Procedure: The catalase activity of the hemolysate is determined by adopting the method of Brannan et.al. The assay is based on the disappearance of H2O2 in the presence of the enzyme source at 26 à ¡Ã‚ ´Ã‚ ¼C. In brief the hemolysate is prepared from lysed RBC suspension, further dilute by phosphate buffer(pH-7.0) Here the reaction mixture containing 0.05M phosphate buffer (pH-7.0), 1.2mM H2O2 and 0.2ml of diluted hemolysate is allowed to stand for 25 min. At the end of which reaction is stopped by the addition of 2.5 ml peroxidase reagent containing peroxidase and the red coloured compound chromogen system. Peroxidase reduced the H2O2 to give a compound and absorbance measure at 505 nm. Calculation: Activity= Std Conc.= 20 µ mol Std.OD =0.02 Unit=  µ mol/minute/mg protein Normal range: 3-5 unit/mg protein STATISTICAL ANALYSIS OF THE DATA: The results were analyzed using Duncan multiple range test. All the data are expressed as mean. Differences between the groups were considered significant at pË‚0.05